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"Pray without ceasing" in the Bible: 1 Thessalonians 5:16-18
Is it really possible to pray without ceasing, and to give thanks in all circumstances? Most of us can probably think of situations in which it would be very difficult to praise God; but the Bible teaches us that through Christ, it is possible to maintain a spirit of praise and thankfulness in even the most trying circumstances.

http://biblegateway.com/passage/?search=1%20Thessalonians%205:16-18&version=NIV