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Lips - a Christian perspective
The prophet Isaiah's call into ministry is a fascinating one. Responding to God's call, he confesses that his lips are unclean and unworthy of the message God wants him to preach. God cleanses his lips and sends him forth as a prophet.

http://biblegateway.com/passage/?search=Isaiah%206:1-7&version=NIV

Mouth in the Bible: James 3:1-12
Watching our words and speech is a major theme in the Bible. This passage describes the importance (and difficulty) of gaining control of our tongues. Words have more power over us and others than we care to admit, so it's critical that what comes out of our mouths is praiseworthy.

http://biblegateway.com/passage/?search=James%203:1-12&version=NIV